Diabetes is a very common disease today. Millions of people around the world suffer from this disease. And in present time Type 2 Diabetes case growing Fast Due to our lifestyle, or just as it can be hereditary. Various drugs are available in the market for the treatment of diabetes.
However, not all patients can be treated with existing medicines, as many of these medicines also have side effects.
Most patients with type 2 diabetes are overweight, due to the build-up of fat around their liver. Because of this, they acquire sensitivity to insulin, which prevents the maintenance of blood sugar levels. There are many other such obstacles that make accurate diabetes treatment difficult.
Researchers recently described
Scientists find cure for type 2 diabetes
A new approach to treating type 2 diabetes is being developed at the Technion, using an autograph of muscle cells designed to absorb sugar at an increased rate.
The disease, caused by insulin resistance and the reduced ability of cells to absorb sugar, is characterized by high blood sugar. Its long-term Complications include heart disease, stroke, damage to the retina which can lead to blindness, kidney failure, and poor blood flow in the limbs which can lead to limb damage.
For amputations. He’s currently being treated with a combination of lifestyle changes, medication, and insulin injections, but is ultimately linked with a 10-year-old. Reduced life expectancy.
Scientists find cure
Led by Prof. Shulamit Levenberg, Ph.D. student Rita Beckerman from the Stem Cell and Tissue Engineering Laboratory at the Technion’s Faculty of Biomedicine.
Engineering presents a new approach to treatment that uses an autograph of muscle cells designed to absorb sugar at an increased rate. Mice treated this way showed normal blood sugar for several months after a single procedure.
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How it Will Work for type 2 Diabetes Patient
Muscle cells are one of the main targets for insulin, and they need to take up sugar from the blood. In their study, Prof. Levenberg Muscle Group mouse cells and engineered these cells to present multiple insulin-activated sugar transporters (GLUT4).
These cells were then cultured to form a built muscle tissue and eventually transported to the stomachs of diabetic mice. The altered cells not only continued to properly absorb sugar, which improved blood sugar levels, but also induced better absorption in other muscle cells of mice, using signals sent between them.
After this one treatment, the mice remained cured of diabetes for four months – the entire time they were under observation. Their blood sugar levels stayed lower, and they had reduced fat levels. Liver, which usually appears in type 2 diabetes.
“By taking cells from the patient and processing them, we eliminate the risk of rejection,” explained Professor Levenberg. These cells can be easily reintegrated into be part of the body and respond to the body’s signalling activity.
Currently, about 34 million Americans, just over 1 in 10, have diabetes, 90% of whom have type 2 diabetes. One treatment that works – and one that is ad hoc treatment rather than daily medication – could dramatically improve both the quality of life and the life expectancy of people with diabetes. The same
The method can also be used to treat various disorders due to enzyme deficiency.
The implanted structure: the modified muscle fibres (in red) express GLUT4 (in green)
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This work was funded by Rina and Avner Schneur as part of the Rina and Avner Schneur Center for Diabetes Research. Rita Beckerman is an Ariane de Rothschild Women’s doctoral program.